Remedy and Way of life Might Decrease Breast Most cancers Danger

Medication and Lifestyle May Lower Breast Cancer Risk

Unfortunately, two long-known protective factors – premature birth (in teens and at the age of 20) and prolonged breastfeeding – have a direct impact on the goals in life of many modern women pursuing university degrees and career advancement, as well as young women who are financially inept are able to be a family.

Many older women are faced with another confusing and controversial decision: whether and for how long hormone therapy is needed to counteract life-threatening symptoms of menopause. Subject to a previous history of breast cancer, women who have not had a hysterectomy are currently advised to take combined hormone therapy (i.e., estrogen and progestin) as briefly as necessary to control symptoms, but no longer than a few years.

A recent July 28 study published in JAMA described the long-term effects on breast cancer risk in 27,347 postmenopausal women who were randomly or not to receive hormone replacement. The authors, led by Dr. Rowan T. Chlebowski of UCLA Medical Center checked the health of the participating women more than two decades later.

Among the 10,739 women who had no uterus and could safely take estrogen alone (progestin is usually added to prevent uterine cancer), menopausal hormone therapy significantly reduced the risk of developing and dying from breast cancer. Among the 16,608 women with a uterus who received combination hormone therapy, the incidence of breast cancer was significantly higher, although there was no increased risk of death from the disease.

Dr. Christina A. Minami, a breast cancer surgeon at Brigham and Women & # 39; s Hospital, and Dr. Rachel A. Freedman, an oncologist at the Dana-Farber Cancer Center, commented on these findings, writing that the new findings “are unlikely to lead to the use of hormone therapy for the sole purpose of reducing breast cancer risk. "

But Dr. Freedman said in an interview: "When I counsel a patient who is genuinely suffering from menopausal symptoms and only eligible for estrogen, these results are reassuring that her risk of breast cancer will not be higher over time."

Then there is the option of taking a daily medication to suppress potential breast cancer in high-risk women who have not yet had the disease. Dr. Jeffrey A. Tice, an internist at the University of California at San Francisco, suggested that female doctors use one of the various risk assessment calculators to determine how likely the patient is to develop breast cancer within the next five or ten years.


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